To support the next phase of collaborative research, NPMSC has launched four new key concept working groups. These groups bring together experts from across institutions to focus on some of the most important questions in pediatric multiple sclerosis, including how the disease begins (onset), how the brain repairs itself (remyelination), how the disease changes over time (progression), and how it affects thinking and memory (cognition).

Each group is working to identify important gaps in knowledge and develop new research ideas to address them. By focusing on these key areas, the Network can move more quickly toward discoveries that improve care and outcomes for children and families affected by MS.

Importantly, these working groups include participants from many NPMSC member sites—not just the core steering committee. This broader involvement strengthens collaboration across the Network and brings a wider range of perspectives and expertise to the table.

This work also aligns closely with the National MS Society’s Pathways to Cures roadmap, which focuses on stopping disease activity, repairing damage to the nervous system, and ultimately preventing MS. The efforts of these working groups directly support those shared goals.

Across all four groups, participants work together to:

    • Identify emerging research priorities
    • Develop strong, high-impact study ideas
    • Support the development of competitive research funding proposals

This structured, collaborative approach helps ensure that NPMSC remains forward-looking and well-positioned to advance meaningful research. By working together and aligning with broader efforts in the MS research community, the Network continues to build momentum toward better treatments and improved outcomes for children with MS.